Based on the duration of insulin action, insulin preparations can be categorized into ultrashort-acting, short-acting, intermediate-acting, long-acting and premixed varieties.

The injection sites for insulin can be chosen from the abdomen, upper and outer arms, front as well as outer thighs and buttocks, but the recommended injection sites for different types of insulin are different. I'll give you a quick overview of where different insulins should be injected.

1. Ultra-short-acting insulin

(1) The absorption rate of ultra-short-acting insulin is not affected by the site of injection and can be administered by injection at regular injection sites (all sites suitable for insulin injection);

 

(2) Intramuscular administration of such drugs is not recommended, despite studies showing that ultrashort is absorbed at similar rates in adipose tissue and muscle tissue in the non-exercise state;

 

2. Short-acting insulin

Short-acting insulin is absorbed faster in the abdomen, so the abdomen is the preferred injection site for short-acting insulin.

3. Intermediate-acting insulin

(1) Intramuscular injection of intermediate-acting insulin should be avoided in order to avoid severe hypoglycemic reactions due to rapid absorption;

(2) Insulin is absorbed more slowly in the thighs and buttocks, so when intermediate-acting insulin is used as basal insulin, its preferred injection sites are the thighs and buttocks;

(3) To reduce the risk of nocturnal hypoglycemia, when possible, single-use intermediate-acting insulin should be administered at bedtime and avoided at dinner.

4. Long-acting insulin and its analogs

(1) To prevent severe hypoglycemic reactions from occurring, intramuscular injections of long-acting insulin and long-acting insulin analogs should be avoided;

(2) Hypoglycemic warnings must be given to patients who exercise after receiving long-acting insulin injections;

(3) Long-acting insulin analogs can be administered at all routine injection sites, but more in-depth studies are needed.

5. Premixed insulin and premixed insulin analogs

(1) When injecting a premixed insulin preparation of regular (short-acting) insulin/NPH (intermediate-acting insulin) before breakfast, the preferred site of injection is the abdomen to accelerate the absorption of regular (short-acting) insulin and to facilitate control of blood glucose fluctuations after breakfast;

(2) When injecting any premixed insulin preparation containing NPH before dinner, the preferred site of injection is the buttocks or anterior thighs to delay the absorption of NPH and reduce the incidence of nocturnal hypoglycemia.

The information is from the Internet and is for reference only.